• Beihang University, China
  • Title:An Efficient Approach to Analysis of Plane Strain Bending Under Tension at Large Strains
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Abstract:
All sheet forming processes incorporate some bending. Therefore, the development of efficient methods of analysis and design of the process of bending under tension at large strains is of great importance for this area of applications. In the present paper, a uniform analysis of plane-strain bending under tension for different rigid/ and elastic/plastic constitutive laws is performed. The analysis is based on the mapping between Lagrangian and Eulerian coordinates. This mapping automatically satisfies the equation of incompressibility and many boundary conditions involved in the boundary value problem for the process of bending under tension at large strains. In most cases numerical treatment is reduced to solving an ordinary differential equation. The solutions obtained either coincide with known exact solutions or show the same tendencies as known approximate solutions. In addition, new solutions are obtained, including an elastic/plastic solution at large strains. The through thickness distribution of the principal stresses and the variation of the bending moment as well as the thickness of the layer with a time-like parameter are illustrated. The distribution of residual stresses and strains is also found assuming the process of unloading is purely elastic.

Biography:
Sergei Alexandrov is a Professor at Beihang University (Beijing, China) under the program “Recruitment Program for Global Experts”, a Research Professor at the Institute for Problems in Mechanics of the Russian Academy of Sciences (Moscow, Russia) and an adjunct faculty member of Ton Duc Thang University (Ho Chi Minh City, Vietnam). He received his Ph.D. in Physics and Mathematics in 1990 and D.Sc. in Physics and Mathematics in 1994. He is a member of the Russian National Committee on Theoretical and Applied Mechanics. Sergei Alexandrov has published more than 400 papers in journals, books and conference proceedings, including three monographs and around 230 papers in journals indexed in the Web of Science. He has participated in the scientific committee of several international conferences and served as a reviewer in a wide range of international journals. He is on the editorial board of several journals including Continuum Mechanics and Thermodynamics (Springer), Structural Engineering and Mechanics (Technopress) and Symmetry (MDPI). His research areas are plasticity theory, fracture mechanics, and their applications to metal forming and structural mechanics.

  • China University of Petroleum (east china), China,
  • Title:Inherently fluorescent polystyrene microspheres for coating, cellular imaging and sensitive detection
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Abstract:
Commercially available polystyrene (PS) fluorescent microspheres have many applications in cell tracing, in vivo imaging, calibration of flow cytometry, and fluorescent probes, etc. However, these particles do suffer from some drawbacks such as the leakage and photobleaching of organic dyes within them. are widely used in biological field for tracing, in vivo imaging and calibration of flow cytometry, among other applications. Here we find that a simple chloromethylation or amination endows the polystyrene particles with inherent fluorescence without any subsequent conjugation of an external fluorophore. No photobleaching or leaking issues were observed in these particles owing to their stable structure.
Chloromethylated PS microspheres (PS-Cl) can keep their perpetual blue fluorescence even in dry powder state making them attractive as a potential coating material. After futther PEGylation, the fluorescent microspheres showed good biocompatibility and negligible cytotoxicity, and could be used to image intracellular Fe3+ due to the selective fluorescence quenching effect of aqueous Fe3+in cytoplasm.
Fluorescent aminated polystyrene microspheres (PS-NH2) can serve as a selective and sensitive fluorescence (FL) probe for the determination of chromium (VI) (Cr(VI)) and mercury (II) (Hg2+) ions in real water samples. Two possible FL quenching mechanisms were proposed for Cr(VI) and Hg2+. The mutual interference of Cr(VI) and Hg2+ in water samples can be negligible by adding two masking reagents, thiourea and BaCl2, respectively. As a result, PS-NH2 could analyze Cr(VI) and Hg2+ separately in water samples with high sensitivity and good accuracy in the range of 0.01–1 μM. The detection limits for Cr(VI) and Hg2+ were 9.1 nM and 9.9 nM, respectively.

Biography:
Dr Qu Jianbo has completed his PhD at the age of 35 years from Institute of Process Engineering,Chinese Academy of Sciences. He is now working as an associate professor and director in Center for Bioengineering and Biotechnology, China University of Petroleum (East China). His research mainly focuses on high-speed protein chromatography supports, multifunctional nanoparticles and porous materials, and controlled/living radical polymerization methods. He has obtained 7 national invention patents, and published more than 25 papers in reputed journals such as Advanced Functional Materials, Macromolecules, ACS Applied Materials and Interface, Sensors & Actuators B, etc.

  • Henan University of Technology, China
  • Title:Influence of Packaging Materials on Infestation by Tribolium castaneum (Herbst) in Wheat Flour
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Abstract:
The influence of packaging materials on infestation by Tribolium castaneum (Herbst) in wheat flour was investigated in laboratory at 27± 2℃ and 75±5% r.h. The tested packaging materials included vacuum plastic bags, aluminum foil bags, nonwoven cloth bags, kraft paper bags, and plastic compound bags. When T. castaneum adults were released on packaged wheat flours, the degree of infestation varied depending on the packaging materials. The highest infestation was observed in refined wheat flour packaged with plastic compound bags (mean 46 insects). For the flour packaged with nonwoven cloth bag and kraft paper bags exposed to adults, insect infestation was nil or negligible (mean population < 3.33 insects). For the flour packaged with aluminum foil bags and vacuum plastic bags exposed to adults, insect infestation was nil. Damage to the packaging materials along the edges or on the upper surfaces was observed in nonwoven cloth bags and plastic compound bags. Aluminum foil bags and vacuum plastic bags had the strongest defence capability against T. castaneum adults. The results indicate that choosing suitable packaging materials can effectively prevent wheat flour from T. castaneum adults infestation.                       Biography: Dr. Jianhua Lü, A professor from School of Food Science and Technology, Henan University of Technology, mainly researching integrated pest management for stored product insect, insect-resistant packaging material.

  • University of Duisburg-Essen, Germany
  • Title:Laser-induced melting and fusion of particles on the sub-micrometer and nanometer scale
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Abstract
Possibilities to change particle properties by pulsed laser irradiation in liquids are manifold. First reported by Henglein and Fojtik [1], this method has proven, not only to change sizes of the irradiated particles [2], but also their chemical composition [3]. Utilizing an optimized set-up enables up-scaling of laser fragmentation [4] and laser melting [5] when enough laser power is available. The specific power input and number of pulses per particle can be derived what enables balancing of the process. The design also allows determination of the laser fluence correlated process window for the particle processing, due to confinement of the particles in the liquid jet. This gives access to scaling parameters to increase the throughput with sufficient laser power, for fabrication of promising hybrid materials [5] and activated materials for catalysis [6] on the sub-micrometer and nanometer scale formed by laser irradiation.

Biography:
Dr. Marcus Lau received his Ph.D. degree in the field of industrial chemistry for his research on laser fragmentation and melting of particles. His research university research period included cooperation and research stays at the University of Tsukuba, Japan and the California Institute of Technology, United States. Since 2017 he works in the field of Scientific Laser Application for TRUMPF GmbH + Co. KG, one of the world leading companies for machine tools, lasers and electronics for industrial applications.

  • Tanta University Hospitals, Egypt
  • Title:Ilizarov distraction osteogenesis over the preexisting nail for treatment of nonunited femurs with significant shortening
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Abstract
Purpose Nonunion of the femur with significant shortening with retained intramedullary nail (IMN) is a challenging orthopedic problem. We investigated whether the application of Ilizarov distraction osteogenesis over the preexisting nail can simultaneously achieve union and correct shortening.
Methods Thirteen patients with femoral diaphyseal nonunion associated with significant shortening with retained IMN were retrospectively reviewed. All patients were treated by distraction osteogenesis using a circular external fixator over the preexisting nail. The fixator was used to compress or distract the nonunion site and to gradually distract a separate osteotomy to restore limb length. The osteotomy was done percutaneously using the Gigli saw with the nail in situ. The applied surgical technique was bifocal compression distraction in 11 cases, bifocal distraction in one case, and monofocal distraction in one case.
Results Bone healing was achieved in 11 cases (84.6 %) at both the nonunion and the lengthening sites. The mean length gained was 4 cm (range, 3–6 cm). The mean time to fracture union was 4.9 months (range, 4–6 months). The mean knee flexion improved from 86.5 (range, 40-135) preoperatively to 109.6 (range, 60–125) at final follow-up (p<0.05). The mean limb-length discrepancy improved from 4.7 cm (range, 3–7.5) preoperatively to 0.7 cm (range, 0–3) at final follow-up (p<0.001). Ten out of 13 patients had a total of 14 complications, with a mean of 1.1 complications per patient. Conclusions Distraction osteogenesis over the preexisting nail can be a good alternative to treat difficult femoral diaphyseal nonunions associated with significant shortening.                                                                                                                                        Biography:                                                                                                                                       Wael Azzam is an Assistant Professor of Orthopedic Surgery and Traumatology, Faculty of medicine, University of Tanta, Egypt, and Head of Orthopedic Department, Gama Hospital, Al Khobar, Kingdom of Saudi Arabia.

  • Stevens Institute of Technology, USA
  • Title:Develop Sustainable and Smart Infrastructure through Innovations and Applications of Fiber Optic Sensors and Multi-functional Materials
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Abstract:
Climate change has triggered wide-range impacts on civil infrastructure and affects the quality of life. While scaling-up infrastructure represents a climate adaptation effort, it may exacerbate climate change, since construction of infrastructure involves significant energy consumption and carbon emission. Sustainable and smart infrastructure has potential to synergize climate change adaptation and mitigation efforts. This presentation will introduce efforts in sensors and materials for development of sustainable and smart infrastructure. To begin with, recent advances in fiber optic sensors for infrastructure applications will be presented. The research innovates in three fronts. First, mechanical and thermo-mechanical models are developed for distributed fiber optic sensor to understand the sensor data at normal and high temperatures. A novel approach to enhancing the sensor’s thermal stability is developed. Second, distributed fiber optic sensors are applied to assess condition and understand degradation mechanisms of structures under mechanical and thermal loadings. Third, a novel fiber optic corrosion sensor is developed through micro-fabrication and thin-film deposition for in-situ monitoring of corrosion. Recently, fiber optic sensors are applied for real-time monitoring and control in building-scale 3D printing using engineered cementitious composites (ECCs). ECCs have been developed with inherent strain-hardening and multi-functionality, such as self-sensing, self-healing, and self-cleaning, and tailored for 3D printing of infrastructure with improved sustainability, durability, resilience, and multi-functionality. ECCs are also applied in innovative design of reconfigurable structures adaptive to digital construction.
Biography:
Dr. Yi Bao is an Assistant Professor in the Department of Civil, Environmental and Ocean Engineering at Stevens Institute of Technology. Prior to joining Stevens, Dr. Bao was a Research Fellow in the Department of Civil and Environmental Engineering at the University of Michigan – Ann Arbor, Michigan, and Guest Researcher at the National Institute of Standards and Technology (NIST) in Gaithersburg, Maryland. Dr. Bao received his Ph.D. degree from Missouri University of Science and Technology, Rolla, Missouri, and was appointed the Inaugural Franklin Y. Cheng Scholar and the Dean’s Scholar. Dr. Bao has expertise in multifunctional cementitious composites, smart materials and sensors for structural health monitoring, innovative structures, and automation in construction. To date, Dr. Bao has published over 70 peer-reviewed journal papers. Dr. Bao is a member of ASCE, ASME, ACI, SPIE, ISHMI, and New York Science Academy, and the recipient of numerous prestigious awards from ASCE and ASME.

  • RMIT University, Australia
  • Title:Biocompatible MgZrSr-REE Alloys for Biodegradable Implant Materials
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Abstract:
Magnesium (Mg) based alloys have been extensively considered for their use as biodegradable implant materials. However, controlling their corrosion rate in the physiological environment of the human body is still a significant challenge. One of the most effective approaches to address this challenge is to strategically design new Mg alloys with enhanced corrosion resistance, biocompatibility, and mechanical properties. Our research has developed new series of Mg-zirconium (Zr)-strontium (Sr)-rare earth element (REE) alloys for biodegradable implant applications. Research results indicate that Sr and Zr additions can refine the grain size and enhance the corrosion and biological behaviors of the Mg alloys. Furthermore, the REE addition such as holmium (Ho) and dysprosium (Dy) to Mg-Zr-Sr alloys resulted in enhanced mechanical strength and decreased degradation rate. In addition, less than 5 wt.% Ho and Dy additions to Mg-Zr-Sr alloys led to enhancement of cell adhesion and proliferation of osteoblast cells on the Mg-Zr-Sr-Ho/Dy alloys. The effect of other REEs such as yttrium (Y) and scandium (Sc) on the mechanical properties, corrosion behaviors and biocompatibility of biodegradable Mg-based alloys/composites will also be discussed.

Biography:
Dr Yuncang Li obtained his Bachelor of Science form Peking University, China and PhD in Materials Science Engineering from Deakin University, Australia. After working in the field of Biomaterials Engineering for over 10 years at Deakin University, he joined RMIT University in 2015. He is an Australian Research Council (ARC) Future Fellow and Associate Professor at the School of Engineering, RMIT University. Dr Li has won a number of national competitive grants including ARC Discovery project and Future Fellowships, and National Health and Medical Research Council (NHMRC) project. His research focuses on developing metallic biomaterials for medical applications. He has expertise in microstructure-mechanical property relationships, corrosion, and biocompatibility, surface modification, nanostructured metals and alloys, and metal foams. He published over 200 peer-reviewed publications and filed 5 patents.

  • China University of Petroleum, China
  • Title:Surficial and Interfacial Modification and Design of Mesoscopic Functional Materials
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Abstract:
Mesoscopic functional materials are distinguished due to which scales are among macroscopic and microscopic. The unique surficial structures and spatial confinement effects endow them with a wide range of applications in the fields of adsorption, separation, photocatalysis, energy conversion, and biological applications. Conversely, at the level of molecule, how to realize the surficial and interfacial modification of mesoscopic functional materials and obtain quality mesoscopic functional structures with superior structural properties remains a challenging topic.The main intentions of this research concentrate on novel synthesis routes of mesoscopic functional materials and corresponding structure-induced applications. A series of mesoscopic materials were prepared, including mesoscopic semiconductor materials, porous adsorptive materials, and three-dimensional (3D) hierarchical materials. Adopted synthetic strategies were used to construct mesoscopic materials with tunable morphologies, surfacial and interfacical properties. Besides, as-made products possess superior functionalities in nanocatalysis , enviromental treatment and energy storage and conversion. The instiric channels and pores can be modified by synthesis routes, resulting ingeneious performance of materials in aforementioned applications. Suficial and interficial modifications contributes actively to the extension of unique properties in meso-scale. Furthermore, the chemical homogeneity, mesostructure, defect states and surface & interface synergistic mechanisms were fully revealed by characterization methods and computational simulation .Apart from it, the transport and coupling mechanisms of electrons, ions, photons, and molecules were explored at the mesoscopic scale, novel physical phenomena arising from the elimination and utilization of surface/interface defects and the mesostructure of self-assembly were discovered, and the new properties and applications of mesoscopic functional materials were developed. (Up to 250 words)

Biography:
Prof. Yan Zi-Feng is currently the Chair Professor of State Key Laboratory of Heavy Oil Processing, PetroChina Key Laboratory of Catalysis, and a founding Professor of the Department of Chemical Material and Industrial Catalysis at the China University of Petroleum. Professor Yan Zi-Feng has successfully supervised and is supervising more than 50 PhD and 100 Master students, and has more than 500 technical publications (H-index, 50) and confidential client reports. He has made significant contributions to adsorption, catalysis and nanomaterials R&D and practices include international understanding of dry reforming of natural gas for syn-gas and hydrogen production and CO2 capture technologies; natural gas / hydrogen adsorption storage; fluidised-catalytic cracking catalysis and gasification of solid fuels (coal and biomass) among many other areas of research. Prof. Yan Zi-Feng was awarded the Shandong Province Research Excellence Awards in 1997, 1999, 2002, 2007, 2011, 2013, and 2016 for his work on catalysis for heavy oil processing and new carbon materials, and the Top Foreign Researchers in nanotechnology by Islamic Republic of Iran in 2008 and Cognizure Prof. Joseph Wang Award in 2015.

  • Teikyo University Medical School, Japan
  • Title:Successful Application of Liquid Cell Electron Microscopy for Studies on the Molecular Mechanism of Muscle Contraction: Results and Implications
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Abstract:
Although muscle contraction is generally believed to result from relative sliding between actin and myosin filaments, coupled with ATP hydrolysis,
Myosin head power and recovery strokes producing the myofilament sliding can not yet be proved by chemical probe and X-ray diffraction techniques, because of asynchronous nature of myosin head motion. Up to the present time, we are the only research group to make it possible to visualize and record individual ATP-coupled myosin head power and recovery strokes in wet, living myosin filaments, using the technique of liquid cell electron microscopy. Here, I will describe novel features of myosin head strokes, revealed by us, and will discuss implications of our results, which constitutes evidence against the current dogma of muscle contraction.

Biography:
Haruo Sugi graduated from post-graduate school in the University of Toky with the degree od Ph.D in 1962, and was appointed to be an instructor in physiology in the University of Tokyo Medical School. From 1965 to 1966,
Sugi worked in Columbia University as a research associate, and from 1966 to 1967, worked in the National Institutes of Health as a visiting scientist. In 1973, He was appointed to be professor and Chairman in the Department of Physiology, Teikyo University Medical School. Sugi retired from Teikyo University in 2004 when he became Emeritus Professor. From 1995 to 2005, Sugi was chairman of Muscle Commission in the International Union of Physiological Sciences (IUPS).

  • University of Lyon, France
  • Title:Impact of cerium oxide nanoparticles shape on their in vitro cellular toxicity
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Abstract:
Cerium oxides (CeO2) nanoparticles, also referred to as nanoceria, are extensively used with a wide range of applications. However, their impact on human health and on the environment is not fully elucidated. The aim of this study was to investigate the influence of the CeO2 nanoparticles morphology on their in vitro toxicity. CeO2 nanoparticles of similar chemical composition and crystallinity were synthesized, only the shape varied (rods or octahedrons/cubes). Macrophages from the RAW264.7 cell line were exposed to these different samples and the toxicity was evaluated in terms of lactate dehydrogenase (LDH) release, Tumor Necrosis Factor alpha (TNF-a) production and reactive oxygen species (ROS) generation. Results showed no ROS production, whatever the nanoparticle shape. The LDH release and the TNF-a production were significantly and dose-dependently enhanced by rod-like nanoparticles, whereas they did not vary with cubic/octahedral nanoparticles. In conclusion, a strong impact of CeO2 nanoparticle morphology on their in vitro toxicity was clearly demonstrated, underscoring that nanoceria shape should be carefully taken in consideration, especially in a “safer by design” context.

Biography:
Jérémie Pourchez received his Ph.D. in Chemical and Process Engineering in 2006. He is Professor since 2012 in the Center for Health Engineering at Ecole Nationale Supérieure des Mines de Saint-Etienne in France. His research interest and teaching include the understanding of inhaled nanoparticles fate within the organism to highlight toxicity, biodistribution and biopersistance of nanoparticles in living systems. His fields of expertise are: anatomic and cell targets of nanosized aerosol, physico-chemistry of nanoparticles and in vitro analysis of biological effects.

  • Georgetown University School of Medicine, USA
  • Title:Anemia in the setting of Chronic Kidney
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Abstract:
Anemia is a well-known complicating feature of chronic kidney disease (CKD) and typically correlates directly with the degree of renal impairment. Both anemia and CKD are common under-recognized and undertreated conditions with significant effects on morbidity and mortality in the elderly. This presentation will focus on specific issues relating to the diagnosis, impact, and treatment of CKD-related anemia in the elderly (although implications typically generalize to younger patients).
The principal underlying etiology of CKD-related anemia is impaired synthesis of the glycoprotein hormone erythropoietin (EPO), which is produced primarily by the cortical fibroblasts adjacent to the peritubular capillaries of the proximal convoluted tubules. Other important contributing factors include iron deficiency, chronic inflammation and malnutrition, each of which is more likely to occur in the elderly. The pathophysiologic basis for anemia related to CKD in older individuals is likely similar to that of younger subjects, complicated perhaps by a greater impact of underlying inflammatory processes, and in men, an age-related decline in testosterone levels. In the general elderly population with CKD, anemia has clearly been associated with reduced quality of life, increased hospitalization risk, longer hospital stays, functional decline, greater cardiovascular and cerebrovascular disease burden and increased mortality
Elderly patients with CKD, whether on hemodialysis or not, should be evaluated and treated for their anemia. Recombinant human erythropoietin (Epoetin) therapy has revolutionized the treatment of anemia in this setting. As a group, the erythroid stimulating agents (ESAs) have proven to be quite safe although early concerns were raised about the possibility of enhanced tumor proliferative properties causing the US Food and Drug Administration warnings and more restricted use in cancer patients. A number of other studies have shown an increased risk of cardiovascular and cerebrovascular side effects in those patients with targeted Hb levels of equal to or greater than 12gm/dl. These studies will be briefly reviewed and critiqued with review of Nephrological governing bodies and personal recommendations as to the optimal targets for these patients: most ESA-treated patients with CKD should therefore have their Hgb levels maintained above 10.0 g/dl but below 12.0g/dl and perhaps lower.
Societal guidelines regarding packed red blood cell transfusions will also be briefly reviewed with similar critiques and personal recommendations. Lastly, exciting new data will be touched upon involving the Hypoxia Inducible Factor Prolyl-Hydroxylase Inhibitors in stimulating erythropoiesis as an alternative to ESAs.

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